| # | Swimmer | Team | Seed | Time | Diff |
| 1 |
Briggs, Emily R (16)
|
MDEST |
2:51.33 |
2:50.01 |
-1.32 |
| 2 |
O'Brien, Peyton M (16)
|
MDMAS |
2:55.09 |
2:52.29 |
-2.80 |
| 3 |
Hopkins, Delaney B (15)
|
MDBAAC |
2:48.38 |
2:53.85 |
5.47 |
| 4 |
Bott, Charlotte E (15)
|
MDLBA |
2:47.76 |
2:55.01 |
7.25 |
| 5 |
Emrich, Kylee M (15)
|
MDSPY |
3:04.65 |
2:57.22 |
-7.43 |
| 6 |
Knauer, Grace E (16)
|
MDSPRC |
3:04.85 |
3:02.38 |
-2.47 |
| 7 |
Yeagle, Alexis L (17)
|
MDEST |
3:04.55 |
3:04.23 |
-0.32 |
| 8 |
Nelson, Sarah L (16)
|
MDBAAC |
2:56.72 |
3:04.47 |
7.75 |
| 9 |
Skvortsova, Margarita (16)
|
MDEST |
3:01.70 |
3:10.50 |
8.80 |
| 10 |
Mazur, Karolina T (15)
|
MDEST |
3:08.41 |
3:11.40 |
2.99 |
| 11 |
Aguirre-Nicholson, Elysia E (17)
|
MDEST |
3:15.83 |
3:11.91 |
-3.92 |
| 12 |
Hines, Nyah E (18)
|
MDEST |
3:08.96 |
3:12.01 |
3.05 |
| 13 |
Harrington, Quinn L (16)
|
MDMAS |
3:25.60 |
3:15.43 |
-10.17 |
| 14 |
Balcer, Rachel V (15)
|
MDHSST |
3:32.31 |
3:21.34 |
-10.97 |
| 15 |
Banks, Diana (15)
|
MDSPRC |
3:22.06 |
3:27.84 |
5.78 |
| 16 |
Bell, Amayah G (15)
|
MDEST |
3:53.90 |
3:47.16 |
-6.74 |
|
Smith, Aria C (17)
|
MDGBSA |
2:47.04 |
NS |
- |
|
Taylor, Anna E (16)
|
MDBAAC |
3:13.83 |
NS |
- |
|
Watson, Lauren S (16)
|
MDMAS |
|
NS |
- |